Endocrine Abstracts

Aim: The aim is to study the clinical and hormonal peculiarities of PROL (prolactinoma), manifesting in people under the age of 18 and monitoring the effectiveness of suppressive CAB (Cabergoline, Dostinex) therapy during 12 months period.Materials and methods: The total study included 11 patients with PROL, manifesting in childhood. There were also examined 54 healthy volunteers (25 males and 29 females) aged 15–19 to determine the range of normal ...

Aim: The aim of the study was to investigate the clinical and hormonal effectiveness of different modes of suppressive cabergoline (CAB) therapy during 12 months in patients with prolactinoma.Subjects and methods: It was examined and underwent a 12 month course of treatment by selective dopamine agonist CAB in 61 patients with prolactinoma (PROL) (9 male/ 52 female) aged 16–66 years. There were 40 women with microPROL, 12 with macro&giant PROL; ...

The aim of the study: To investigate the anti-proliferative effect of cabergoline (CAB) which was used in different regimes of suppressive therapy during 12 months in patients with prolactinoma (PROL).Subjects and methods: It was examined and underwent a 12 month course of treatment by selective dopamine agonist CAB 61 patients with PROL: microadenoma 42, macro&giant PROL - 19. (52 women/9 men) aged 16–66 years. The total duration of the disease...

Introduction: The role of the pineal gland and its hormone, melatonin, in the regulation of hypothalamo-adenohypophysial system activity is well known. At the same time, studies of the circadian rhythm of melatonin secretion in patients with pituitary adenomas are few in number, because the evaluation of pineal activity is not generally included in the clinical investigation of patients with pituitary tumors.Aim: The present study analyzed the circadian ...